Wicomico County, Maryland
Salisbury, MD Homes & Real Estate
The Eastern Shore hub at the crossroads of Route 13 and Route 50.
Salisbury is the largest city on Maryland’s Eastern Shore and the county seat of Wicomico County. It sits on the Wicomico River at the crossroads of US-13 and US-50 and serves as the region’s center for healthcare, retail, higher education and business.
US-13 runs north toward Dover and south toward Virginia’s Eastern Shore, and US-50 heads east to Ocean City and west toward Cambridge and the Chesapeake Bay Bridge. Delmar and the Delaware line are a short drive south, and Salisbury–Ocean City–Wicomico Regional Airport offers commercial flights. The beaches at Ocean City and Delaware’s Rehoboth Beach are a drive to the east.
TidalHealth Peninsula Regional, the main hospital on the lower Shore, and Perdue Farms, whose headquarters is in Salisbury, are among the area’s largest employers. Riverwalk Park and the Wicomico River give residents a place to walk downtown, and the Salisbury Zoo and the Ward Museum of Wildfowl Art are also in the city. Shopping centers line Route 13 and Route 50.
Housing includes older homes in and near the downtown historic areas, apartments and townhomes, single-family neighborhoods built over many decades, and newer subdivisions on the edges. Community fees and lot size vary, and homes just across the line in Delmar can have different taxes. We lay these out for each address. Browse the nearby listings or ask for a free home value.
Salisbury is a larger market than most Eastern Shore towns, so prices and conditions differ between neighborhoods near downtown, around the hospital and out toward Route 50. We keep the comparison local by using recent sales on nearby streets. If a commute or a move to the Delaware side matters to you, we can also compare homes just across the line in Delmar, where property taxes and services differ, and put the numbers side by side.
- County
- Wicomico County, Maryland
- Main routes
- US-13, US-50
- Employers
- TidalHealth Peninsula Regional, Perdue Farms
- Nearby
- Ocean City, Delmar, Rehoboth Beach
Homes in and near Salisbury
Next steps
Buy in Salisbury: tell us what you want and we’ll send matching homes with a cost estimate. Sell your home: a pricing plan and net sheet before you list. Free home value: a local, agent-prepared estimate. Browse all areas we serve.
Last updated October 2026. General area information for orientation only; confirm details such as taxes, fees and flood zones for any specific address.